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Evaluation of the Safety and Efficacy of GLK-321 in Subjects With Demodex Blepharitis

Evaluation of the Safety and Efficacy of GLK-321 in Subjects With Demodex Blepharitis

Recruiting
18 years and older
All
Phase 2
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Overview

This is a randomized, double-masked, placebo-controlled, dose-ranging, parallel-group, multi-center study designed to evaluate the safety and efficacy of GLK-321 in patients with Demodex blepharitis.

Eligibility

Inclusion Criteria:

  • Signs of Demodex blepharitis in at least one eye
  • Best Spectacle Corrected Visual Acuity (BSCVA) of 20/80 Snellen or better in each eye

Exclusion Criteria:

  • Presence of eczema or dermatitis in the ocular region of either eye
  • Use of lid hygiene products within 14 days of Screening
  • Active ocular infection or inflammation, other than blepharitis, in either eye at Screening
  • Women who are pregnant, planning a pregnancy, or nursing
  • Have used an investigational drug or device within 30 days prior to Screening or concurrently enrolled in another investigational drug or device trial

Study details
    Demodex Blepharitis

NCT07400965

Glaukos Corporation

14 May 2026

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