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Combined tDCS and Cognitive Training as an Adjunctive Treatment in Opioid Use Disorder

Combined tDCS and Cognitive Training as an Adjunctive Treatment in Opioid Use Disorder

Recruiting
18 years and older
All
Phase N/A

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Overview

The overall goal of this study is to investigate the added benefit of a neuromodulation intervention in individuals under buprenorphine maintenance treatment for OUD (bOUD).

Eligibility

Inclusion Criteria:

  • ability to provide consent and comply with study procedures
  • Diagnostic and Statistical Manual of Mental Disorders criteria for OUD
  • undergoing buprenorphine maintenance treatment. Participants may have current comorbid drug use, but primary diagnosis must be OUD
  • Intention to remain in the addiction treatment program until intervention completion.

Exclusion Criteria:

  • Any medical condition with neurological sequelae
  • head injury resulting in skull fracture or loss of consciousness of \>30 minutes
  • any tDCS or MRI contraindication (tDCS: history of seizures, metallic cranial plates/screws or implanted device, history of eczema on scalp. MRI: unapproved metallic implants, pacemakers or any other implanted electrical device, shrapnel, metallic braces, non-removable body piercings, pregnancy, breathing or movement disorder, or claustrophobia)
  • any psychotic disorder (participants with other treated and stable psychiatric disorders will be included)
  • presence of a condition that would render study measures impossible to administer or interpret
  • age younger than 18
  • primary current substance use disorder on a substance other than opioids except for caffeine or nicotine
  • court mandated treatment
  • pregnancy
  • disrespectful behavior towards the investigators and staff.

Study details
    Opioid Use Disorder
    Buprenorphine

NCT07158853

University of Minnesota

13 May 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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