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A Study of SCAD Using Stress Contrast Echocardiography

A Study of SCAD Using Stress Contrast Echocardiography

Recruiting
18 years and older
All
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

This study aims to fill knowledge gaps regarding microvascular perfusion and pressor response to stress among patients with history of spontaneous coronary artery dissection (SCAD) using stress contrast echocardiography.

Eligibility

Inclusion Criteria:

  • Adult \>18 years old
  • Patient has a history of spontaneous coronary artery dissection (SCAD) OR patient is healthy with no significant medical history

Exclusion Criteria:

  • Unable to give consent
  • Allergic or have a history of adverse reaction to dobutamine, the Definity® ultrasound enhancing agent, or atropine.
  • Has a known or suspected hypersensitivity to perflutren and therefore cannot be given Definity®.
  • Pregnant.
  • Unable to interrupt breastfeeding.
  • Within 3 months of a heart attack.
  • Severe aortic stenosis.
  • Severe, uncontrolled hypertension (\>200/110 mmHg at baseline).

Study details
    Spontaneous Coronary Artery Dissection

NCT07178509

Mayo Clinic

1 February 2026

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