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Clinical Study on the Treatment of Rhinitis Sicca With Sodium Hyaluronate Adjustable Nasal Irrigator

Clinical Study on the Treatment of Rhinitis Sicca With Sodium Hyaluronate Adjustable Nasal Irrigator

Recruiting
18-75 years
All
Phase 4

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Overview

To observe the therapeutic effect of sodium hyaluronate adjustable nasal irrigator on various types of rhinitis sicca and compare it with the therapeutic effect of the commonly used physiological seawater nasal spray in clinical practice.

Eligibility

Inclusion Criteria:

  • Symptoms: Dry nose sensation, little and thick nasal discharge, nosebleeds, itchy nasal cavity, and dryness in the nasopharynx. Physical signs: Nasal endoscopy often reveals dry and congested nasal mucosa, which appears grayish-white or dark red, losing its normal luster. There are often dry, thick secretions, scabs or blood scabs on it. The surface of the nasal mucosa is eroded and ulcers occur. The mucosal lesions are most obvious in the anterior part of the nasal cavity. A diagnosis can be made if one or more of the above symptoms and signs are present.

Exclusion Criteria:

  1. Those with dry rhinitis and chronic inflammation of the lower respiratory tract.
  2. Those confirmed by examination to be caused by certain latent lesions in the mouth, nose, throat, esophagu.s, neck or the whole body
  3. Those who have used drugs for treating dry rhinitis or other medications within the past 30 days.
  4. Pregnant or lactating women.
  5. Those who are allergic to this medicine.
  6. Those with severe cardiovascular, liver, kidney and hematopoietic system diseases, etc.
  7. Mentally ill patients.

Study details
    Rhinitis Sicca

NCT07308015

China-Japan Union Hospital

1 February 2026

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