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Combined Use of Bacteroides Fragilis and BCAAs on HBsAg Clearance

Combined Use of Bacteroides Fragilis and BCAAs on HBsAg Clearance

Recruiting
18 years and older
All
Phase N/A
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Overview

The goal of this prospective observational study is to determine the effects of concomitant administration of Bacteroides fragilis and Branched-Chain Amino Acids on hepatitis B virus clearance. The primary question it aims to answer is whether this concomitant administration can promote HBV clearance.

The study will observe the HBV clearance rate in chronic hepatitis B patients who receive Bacteroides fragilis and BCAA as a supplement to their routine antiviral therapy. For comparison, researchers will compare the clearance rate in this group to that observed in a control group of chronic hepatitis B patients receiving a standard antiviral regimen based on PegIFNα2b and nucleoside analogs.

Eligibility

Inclusion Criteria:

\- chronic hepatitis B patients

Exclusion Criteria:

  • patients with malignancies
  • patients with other liver diseases
  • pregnancy patients

Study details
    Chronic Hepatitis B

NCT07257562

First Affiliated Hospital of Fujian Medical University

1 February 2026

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