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AI Facial Analysis Algorithm to Screening Coronary Artery Disease in High-Risk Community Population

AI Facial Analysis Algorithm to Screening Coronary Artery Disease in High-Risk Community Population

Recruiting
18 years and older
All
Phase N/A

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Overview

This study aims to evaluate the effectiveness of this facial image-based AI algorithm for screening CAD in high-risk community populations (specifically individuals with diabetes, hypertension, or aged over 65). The main objectives are:

  1. To verify if the AI algorithm can accurately distinguish between high-risk and low-risk groups by comparing the actual prevalence of CAD in these groups.
  2. To compare the CAD detection rate using this AI screening strategy against the natural detection rate in a real-world cohort.

Eligibility

Inclusion Criteria:

  • Age \>= 18 years.
  • Community high-risk population, defined as individuals meeting at least one of the following criteria:
    1. Diagnosed with Diabetes Mellitus;
    2. Diagnosed with Hypertension;
    3. Advanced age (\> 65 years old).

Exclusion Criteria:

  • Prior confirmed diagnosis of Coronary Heart Disease (CAD), including clinically diagnosed CAD, history of Coronary Artery Bypass Grafting (CABG), or history of Percutaneous Coronary Intervention (PCI).
  • History of diagnosed Heart Failure.
  • Significant facial alterations or conditions that may interfere with AI image analysis, such as plastic surgery, severe facial trauma, or heavy makeup.
  • Refusal to participate in the study.

Study details
    Coronary Artery Disease (CAD)
    Artificial Intelligence Algorithms
    Face
    Screening

NCT07277686

China National Center for Cardiovascular Diseases

1 February 2026

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