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The Use of Rhythmic Light Therapy in Mild Cognitive Impairment

The Use of Rhythmic Light Therapy in Mild Cognitive Impairment

Recruiting
55-80 years
All
Phase N/A
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Overview

In this within-subjects, crossover study, participants will undergo Electroencephalogram (EEG) recordings before, during, and after each of three 1-hour sessions. All participants will experience all three conditions: (1) dual-frequency visual (10 and 40 Hz), (2) single-frequency visual (40 Hz), and (3) non-rhythmic stimulation. EEG spectral power and amplitude coupling will be analyzed to determine whether stimulation-induced increases in alpha-gamma neural synchrony translate to improvements in cognitive performance.

Eligibility

Inclusion Criteria:

  • History of Mild Cognitive Impairment with a Montreal Cognitive Assessment score between 18 and 25

Exclusion Criteria:

  • History of epilepsy or photosensitivity
  • Blindness or other obstructive vision conditions
  • retinal diseases
  • presence of another brain disease accounting for their cognitive status

Study details
    Mild Cognitive Impairment

NCT07318038

Icahn School of Medicine at Mount Sinai

31 January 2026

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