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NEUROPSYCHOLOGICAL PROFILE CHARACTERIZATION IN PATIENTS WITH MIGRAINE: COGNITIVE FUNCTIONING AND PSYCHOLOGICAL VARIABLES

NEUROPSYCHOLOGICAL PROFILE CHARACTERIZATION IN PATIENTS WITH MIGRAINE: COGNITIVE FUNCTIONING AND PSYCHOLOGICAL VARIABLES

Recruiting
18-65 years
All
Phase N/A

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Overview

The overall objective is to define the neuropsychological profile of patients with migraine and evaluate its association with: psychological outcome measures (anxiety-depressive symptoms, pain catastrophizing, excessive worry, and coping strategies); the clinical profile of migraine; the prodromal, ictal, or interictal phase of the migraine attack; pharmacological therapy; and detoxification treatment in patients with migraine associated with medication overuse headache.

Eligibility

Inclusion Criteria:

  • Written informed consent.
  • Patients aged between 18 and 65 years.
  • Diagnosis of migraine according to the International Classification of Headache Disorders (ICHD-3) criteria.
  • Patients with a history of migraine for at least one year, to ensure the stability of the condition.
  • Stability of ongoing treatment for at least 3 months at baseline.
  • Understanding of the Italian language.

Exclusion Criteria:

  • Severe medical or psychiatric conditions (depression, schizophrenia, psychosis) documented by specific previous diagnoses.
  • A history of alcohol or drug abuse.
  • Primary sensory deficits.

Study details
    Migraine
    Migraine Disease

NCT07233941

Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

31 January 2026

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