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Maintenance Venetoclax in AML Fit Patients

Maintenance Venetoclax in AML Fit Patients

Recruiting
18-60 years
All
Phase N/A
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Overview

this study will explore the efficacy of maintenance SC cytarabine + venetoclax therapy as regard disease free survival (DFS) in AML fit patients who achieved CR after highly aggressive chemotherapy as bridge for BMT or if BMT will be delayed or canceled due to any other reason.

Description

this study is a prospective,phase III , randomized ,open , interventional study include young fit patients who will receive maintenance venetoclax +subcutaneous cytarabine as bridge for BMT or if BMT will be delayed

Eligibility

Inclusion Criteria:

  • Age : 18 - 60 years . Patients who are not eligible for immediate bone marrow transplantation. Newly diagnosed AML patients who attained CR after 1st line. Refractory / recurrant AML patients who attained CR after 2nd line .

Exclusion Criteria:

  • Patients not on CR . Age : younger than 18 or older than 60 . Patients not eligible for bone marrow transplation

Study details
    Acute Myeloid Leukaemia (AML)

NCT07244367

Sohag University

31 January 2026

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