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A Study to Evaluate the Safety and Effectiveness of JUVÉDERM Products in Adult Participants for the Change of Their Overall Facial Appearance

A Study to Evaluate the Safety and Effectiveness of JUVÉDERM Products in Adult Participants for the Change of Their Overall Facial Appearance

Not Recruiting
22-65 years
All
Phase 4

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Overview

The purpose of this study is to evaluate the safety and effectiveness of JUVÉDERM products in adults seeking improvement in facial volume and/or skin quality.

Eligibility

Inclusion Criteria:

  • Must meet at least 3 of the following criteria for treatment in the face with at least 2 JUVÉDERM products, per investigator's assessment:
    • Minimal, moderate, or severe on Allergan Temple Hollowing Scale (ATHS)
    • Moderate or severe for both eyes on Allergan Infraorbital Hollow Scale (AIHS)
    • Moderate or severe on Allergan Cheek Smoothness Scale (ACSS)
    • Moderate, significant, or severe on Mid-face Volume Deficit Scale (MFVDS)
    • Moderate or severe on Nasolabial Fold Severity Scale (NLFSS)
    • Minimal, mild, or moderate on Allergan Lip Fullness Scale 2 (ALFS2)
    • Moderate or severe on Allergan Chin Retrusion Scale (ACRS)
    • Moderate or severe on Allergan Loss of Jawline Definition Scale (ALJDS)
  • Must be in good health as determined by subject's medical history, physical

    examination, and vital sign measurements.

Exclusion Criteria:

  • Prior treatment with non-permanent soft tissue fillers or fat-reducing injectables in the face or neck within 12 months prior to screening.
  • Excessively loose skin in the face and/or neck.
  • Tendency to develop hypertrophic scarring and/or keloid scarring.

Study details
    Mid Face Volume Deficit

NCT07186595

AbbVie

26 February 2026

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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