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Strength-Endurance Circuit Training in Parkinson's Disease

Strength-Endurance Circuit Training in Parkinson's Disease

Recruiting
18-75 years
All
Phase N/A

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Overview

The goal of this clinical trial is to determine whether adding strength training to aerobic training has a comparable or greater effect on the clinical status of Parkinson's disease patients than a standalone aerobic training.

  • Does combined strength-endurance circuit training provide added benefits to physical performance, disease severity, blood biomarkers, and quality of life in PD patients compared to standalone aerobic training?

Participants will:

  • undergo outcome measurements before and after the 12-week intervention and a 3-month follow-up measurement,
  • visit the clinic twice a week for 1-hour training sessions.
  • selected patients will be given a smartwatch with a pedometer that will count their average number of steps before, during and after the training period

Eligibility

Inclusion Criteria:

  • age ≥18 years
  • diagnosis of idiopathic Parkinson´s disease
  • Hoehn-Yahr Scale ≤ 2,5
  • stable dopaminergic medication

Exclusion Criteria:

  • age ≥75 years
  • Hoehn-Yahr Scale ≥ 2,5
  • deep brain stimulation
  • presence of freezing
  • Camptocormia
  • inability to walk without support
  • inability to perform study procedures
  • limiting co-morbidities
  • attendance at training sessions below 70%

Study details
    Parkinson Disease
    Idiopathic

NCT06893055

General University Hospital, Prague

16 October 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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