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Efficacy of Iontophoresis in Treating Lateral Epicondylitis Patients

Efficacy of Iontophoresis in Treating Lateral Epicondylitis Patients

Recruiting
20-50 years
All
Phase 1

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Overview

This study is conducted To evaluate the effect of magnesium sulfate on pain intensity, muscle power, hand grip and function ability in patients with lateral epicondylitis.

Description

This study is conducted To evaluate the effect of magnesium sulfate on pain intensity, muscle power, hand grip and function ability in patients with lateral epicondylitis.

BACKGROUND

Lateral epicondylitis (LE) (tennis elbow) is a tendinopathy of the forearm extensor muscles, often caused by overuse or repetitive use (mostly of the extensor carpi radialis brevis), forced extension or direct trauma in the epicondyle . LE has an approximate rate of 40% and a prevalence of 1-3% of the general population . It mostly affects people 40 years and older. Some studies indicate that men and women are equally affected; others report a higher percentage of affected women .

HYPOTHESES

It will be hypothesized that:

There will be no statistically significant effect of magnesium sulfate on pain intensity, muscle power, hand grip and function ability in patients with lateral epicondylitis.

Definition of terms Lateral epicondylitis: pain and tenderness over the lateral epicondyle of the humerus, and pain on resisted dorsiflexion of the wrist, middle finger, or both .

Iontophoresis: is a technique used to enhance transdermal penetration of substances through the application of electric current .

RESEARCH QUESTION:

This study will be conducted to answer the following question:

What is the effect of magnesium sulfate on pain intensity, muscle power, hand grip and function ability in patients with lateral epicondylitis?

Eligibility

Inclusion Criteria:

  • • Their age will be ranged between 20-50 years with both gender
    • Pain on the lateral side of the elbow for at least 4 weeks
    • Tenderness over the lateral epicondyle
    • At least two positive provocative tests: Mill test and Thomson test

Exclusion Criteria:

  • • History of injection, surgery, physical therapy in the elbow area in the last 3 months
    • Previous elbow surgery
    • History of radius/ulna fracture
    • History of cervical and shoulder problems
    • Having bilateral symptoms
    • Concomitant medial epicondylitis
    • Malignancy
    • Pregnancy
    • Systemic rheumatologic disease or systemic infection
    • Inserted cardiac pacemaker
    • Presence of coagulation disorders
    • Cognitive dysfunction

Study details
    Lateral Epicondylitis

NCT06578000

NOUR ALI ABO EL ELAA FRAGHLY

21 October 2025

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