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Tapse/Pasp General Anesthesia

Tapse/Pasp General Anesthesia

Recruiting
18-75 years
All
Phase N/A

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Overview

TAPSE, one of the methods for evaluating right ventricular systolic function; It is a bar parameter that can easily measure apex-basal shortening and provides specific information about global RV function. TAPSE/PASP can be calculated as load-independent parameters to evaluate RV function. Because RV function is sensitive to change in afterload, known as the RV-pulmonary circulation (PC) connection.

This study aims to identify patients who are candidates for hypotensive events due to general anesthesia in a hemodynamically stable population.

Description

TAPSE, one of the methods for evaluating right ventricular systolic function; It is a bar parameter that can easily measure apex-basal shortening and provides specific information about global RV function. TAPSE/PASP can be calculated as load-independent parameters to evaluate RV function. Because RV function is sensitive to change in afterload, known as the RV-pulmonary circulation (PC) connection.

This study aims to identify patients who are candidates for hypotensive events due to general anesthesia in a hemodynamically stable population.

Patients will be measured by transthoracic echocardiography in the preoperative period, 15-30 minutes before induction.

Basal hemodynamic parameters and non-invasive and/or hemodynamic values will be recorded every two minutes after induction until surgical incision.Patients with a 30% decrease in SBP from the baseline and a decrease in MAP below 65 mmHg in the first 10 minutes after anesthesia induction will be considered to have hypotension. Patients will be divided into 2 groups: 'with' and 'without' hypotension.

Eligibility

Inclusion Criteria:

  1. Written informed consent;
  2. 18-75 years old
  3. ASA Physical Status 1-3;
  4. Patients planned for surgery

Exclusion Criteria:

  1. The patient is pregnant
  2. After cardiac surgery
  3. Severe pulmonary hypertension
  4. Severe valve disease
  5. Hypertrophic or dilated cardiomyopathy
  6. Presence of acute myocardial infarction
  7. Patients with severe visual or hearing impairment/disability
  8. ASA physical status IV or V
  9. Ischemic heart disease, conduction disorder.

Study details
    Hypotension

NCT06414811

Aydin Adnan Menderes University

21 October 2025

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