Overview
This study is a prospective, single-center, randomized controlled trial to compare whether applying nutritional supplementation therapy before and after surgery in elderly patients aged 65 years or older undergoing non-cardiac surgery can reduce the incidence of postoperative delirium.
Eligibility
Inclusion Criteria:
- Elderly patients aged 65 and above.
- Patients undergoing non-cardiac major surgery in thoracic surgery, lung cancer surgery, multi-level spinal surgery in neurosurgery and orthopedics, or liver cancer surgery in hepatobiliary and pancreatic surgery, under general anesthesia with an expected surgery duration of 2 hours or more.
- Patients scheduled for arterial catheterization.
- Patients who are able to take oral intake from postoperative day #1.
Exclusion Criteria:
- Patients with uncontrolled systemic conditions such as diabetes, hypertension, renal disease, liver disease, and other systemic illnesses.
- Those with visual impairment.
- Patients with cognitive impairment based on the Mini-Mental State Examination for Dementia Screening criteria.
- Individuals experiencing difficulty in communication.
- Those diagnosed with neurological disorders (such as brain hemorrhage, stroke, brain tumor, dementia, Parkinson's disease, cognitive impairment, depression, etc.).
- Patients diagnosed with alcohol or substance addiction.
- Patients with cancelled scheduled surgeries.
- Patients undergoing minor surgeries with expected anesthesia durations of less than 2 hours.
