Overview
The purpose of the study is to examine the feasibility and acceptability of an exercise and nutrition "prehabilitation" program for patients preparing for pancreatic cancer resection (removal).
Eligibility
Inclusion Criteria:
- Age 18 years or older
- Biopsy-proven pancreatic ductal adenocarcinoma (PDAC), borderline resectable at diagnosis
- Eastern Cooperative Oncology Group (ECOG) performance status 0-2
- Undergoing neoadjuvant chemotherapy with treatment plan including chemoradiation therapy and surgical resection
- Ability to read and speak English
Exclusion Criteria:
- Regular engagement in RT (2x/week targeting all major muscle groups)
- Screen failure for exercise safety based on PAR-Q
- Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease
- Recent fracture or acute musculoskeletal injury that precludes ability to participate in RT
- Numeric pain rating scale greater than or equal to a 7 out of 10
- Myopathic or rheumatologic disease that impacts physical function