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The TELENEO Trial: A Multicenter Trial of Telemedicine for Advanced Neonatal Resuscitations in Community Hospitals

The TELENEO Trial: A Multicenter Trial of Telemedicine for Advanced Neonatal Resuscitations in Community Hospitals

Recruiting
All
Phase N/A

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Overview

The purpose of this study is to evaluate the impact of real-time audio-video telemedicine consults with a neonatologist (termed teleneonatology) on the early health outcomes of at-risk neonates delivered in community hospitals.

Description

This prospective, multicenter trial will use a stepped wedge cluster randomized study design to evaluate the impact of real-time audio-video telemedicine consults with a neonatologist (termed "teleneonatology") on the risk of early mortality, early morbidity, and delivery room care for at-risk neonates delivered in community hospitals.

Eligibility

Inclusion Criteria:

GROUP 1: Community hospital clinicians

To be eligible to participate in this study, an individual must meet all of the following criteria:

  1. A clinician who attends newborn resuscitations at a participating community hospital spoke site.
  2. Provision of informed oral consent prior to any mandatory study specific procedures and analyses.

GROUP 2: At-risk outborn neonates To be eligible for this study, a neonate born in a participating community hospital spoke site must meet \at least one\ of the following inclusion criteria

  1. Preterm birth at less than 32 weeks' gestation at delivery; OR
  2. Need for advanced resuscitation defined as:
    1. positive pressure ventilation (PPV) initiated soon after birth and continued for at least 10 minutes; OR
    2. placement of an alternative airway (endotracheal tube or laryngeal mask) to provide PPV; OR
    3. chest compressions.

Exclusion Criteria:

GROUP 1: Community hospital clinicians None

GROUP 2: At-risk outborn neonates

A neonate born in a participating community hospital spoke site who meets any of the following criteria will be excluded from the study:

  1. Birth outside of the hospital birthing center.
  2. Neonatal transport team present at time of birth and providing resuscitative care.
  3. Severe congenital anomaly necessitating intensive care or surgery in the first two weeks of life.
  4. Plan for comfort care (non-resuscitation) following delivery.
  5. In-person neonatology-trained physician present for the resuscitation.

Study details
    Death; Neonatal
    Morbidity;Newborn

NCT06087224

Mayo Clinic

13 May 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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