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Genetic Studies of Early-onset Dementia

Genetic Studies of Early-onset Dementia

Recruiting
35 years and older
All
Phase N/A

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Overview

The aim of this study is to identify genetic factors that contribute to risk and progression of early-onset dementia (loss of memory function before the age of 70 years) across all ethnic groups, including Alzheimer's Disease, mild cognitive impairment and other dementias.

Description

The study population includes individuals with Alzheimer's disease, mild cognitive impairment, other forms of dementia, as well as cognitively healthy individuals with a family history of dementia. Participants include males and females across all racial and ethnic groups.

Eligibility

Inclusion criteria:

  • 35 years and older
  • Individuals experiencing memory concerns or diagnosed with dementia and their family members that are unrelated healthy controls without dementia.

Exclusion Criteria:

\- Individuals with competing diagnosis such as Huntington's disease, traumatic brain injury, drug or alcohol abuse, or schizophrenia, etc., unless family members of a dementia affected individual

Study details
    Dementia
    Early Onset
    Alzheimer Dementia (AD)
    Mild Cognitive Impairment (MCI)
    Memory Loss

NCT04906863

Columbia University

13 May 2026

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