Overview
Investigate the effect of a probiotic (live bacteria) and postbiotic (heat-treated bacteria) strains in overweight individuals.
Description
This study aims to investigate the safety and efficacy of live and heat treated bacteria on body composition of overweight individuals. The trial will be run in a single research centre and will recruit adult men and women, with BMI of 25-33kg/m2 with abdominal obesity.
Eligibility
Inclusion Criteria:
- Body mass index 25-33kg/m2
- Abdominal obesity (female waist circumference>85cm; male waist circumference>90cm)
- written informed consent
Exclusion Criteria:
- Taking the following medication within 1 month before starting the study: appetite stimulants/suppressants, lipid lowering drug, contraceptive
- taking antibiotics within 2 months before starting the study
- secondary obesity or secondary hypertension, diabetes type 1, GI disease, dyslipidaemia, type 2diabetes, hypertension
- consumption of pre- and probiotic-enriched products or dietary supplement for at least 4 weeks prior to the first screening visit
- nicotine, drug or alcohol abuse,
- other condition that, in the opinion of the investigators, would make participation not in the best interest of the patient or could prevent, limit or confound the Study's results
