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Edaravone in the Treatment of Optic Neuritis

Edaravone in the Treatment of Optic Neuritis

Recruiting
18-70 years
All
Phase N/A

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Overview

Edaravone has demonstrated a beneficial effect in promoting remyelination and protecting axons in animals with NMOSD. The researchers posit that edaravone may enhance visual outcomes in patients with aquaporin-4 antibody-positive optic neuritis.

Eligibility

Inclusion Criteria:

  1. Chinese patients aged ≥18 with anti-aquaporin-4 antibody-positive optic neuritis
  2. Patients with a first episode of optic neuritis in either eye
  3. First symptoms of optic neuritis ≤30 days prior to the first administration of edaravone

Exclusion Criteria:

  1. Myopia over 6 diopters
  2. Refractive media opacity affecting assessment of retinal layers and/or visual acuity

Study details
    Optic Neuritis

NCT05540262

First Affiliated Hospital of Guangxi Medical University

13 May 2026

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