Overview
This is a prospective single arm single center Phase III study evaluating the ability of 18F-fluorocholine to detect the location of parathyroid adenomas.
Description
PRIMARY OBJECTIVE:
I. To investigate the performance (accuracy) of 18F-fluorocholine PET in the detection of hyperfunctioning parathyroid glands in surgical patients with biochemically proven primary hyperparathyroidism.
- OUTLINE
Participants will receive a single dose of 18F-Fluorocholine at the time the participant undergoes a single imaging study using 18F-fluorocholine. Study related procedures will end after the study visit. Participants who undergo subsequent parathyroidectomy, will have the results reviewed and compared to the results from the imaging study
Eligibility
Inclusion Criteria:
- Age >= 13 years.
- Biochemically proven hyperparathyroidism and an indication for surgery.
- Ability to understand a written informed consent document, and the willingness to sign it.
Exclusion Criteria:
- Current Pregnancy.
- Patients unlikely to comply with study procedures, restrictions and requirements and judged by the Investigator to be unsuitable for study participation.