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Cortical-Basal Ganglia Speech Networks

Cortical-Basal Ganglia Speech Networks

Recruiting
18-85 years
All
Phase N/A
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  • Simplified (AI rewritten)

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Overview

In this research study the researchers want to learn more about brain activity related to speech perception and production.

Description

Speech production is disrupted in a number of neurological diseases that involve the basal ganglia, including Parkinson's disease (PD) and dystonia. The investigators will use a novel experimental approach and combination of analytic techniques to elucidate the contribution of neural activity in cortical-basal ganglia circuits to the hierarchical control of speech production, in subjects undergoing deep brain stimulation surgery.

Eligibility

Inclusion Criteria:

  1. Subjects scheduled for DBS implantation, as determined by the clinical multidisciplinary movement disorders board with definitive diagnosis of Parkinson's disease, essential tremor or dystonia.
  2. Subjects able to provide informed consent and comply with task instructions.
  3. Subjects 18-85 years old

Exclusion Criteria:

  1. Subjects with reported hearing loss.
  2. Non-English-speaking subjects

Study details
    Parkinson Disease
    Essential Tremor
    Dystonia

NCT04286308

Massachusetts General Hospital

27 January 2024

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