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The CARMA Technique Study

The CARMA Technique Study

Recruiting
16 years and older
All
Phase N/A

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Overview

Colonoscopic removal of polyps is an important and well-established tool in the prevention of colorectal cancers. However, high polyp recurrence rates after endoscopic resection, with resultant development of interval cancers, remains a problemÍž this most commonly stems from unrecognised incomplete polyp resection. Thus, a standardised endoscopic technique is needed that will allow endoscopists to consistently achieve a clear margin of resection. The investigators believe the Cap Assisted Resection Margin Assessment (CARMA) technique will address this problem. This novel technique focuses on a standardised assessment of the resection margin after endoscopic polypectomy utilising available standard high-definition video endoscopes with imaging features including narrow band imaging (NBI) and magnification endoscopy.

Eligibility

Patients with colonic polyps will be considered following below criteria

Inclusion Criteria:

  • any polypectomy (though only a maximum of two polyps from one individual participant)

Exclusion Criteria:

  • polyps less than 10mm which were resected under endoscopic view with a definite > 1mm clear margin
  • scar site recurrence polyps
  • polyps with endoscopic evidence of invasion
  • pedunculated polyps
  • pseudopolyps
  • participants who will not be available for follow up endoscopy

Study details
    Colonic Polyp
    Colonic Sessile Serrated Lesion

NCT05099432

Princess Alexandra Hospital, Brisbane, Australia

27 January 2024

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