Overview

The purpose of this study is to see how cancer treatment affects sexual and reproductive function. The patient will also be asked to participate in blood draws to see if and how cancer treatment affects the ovaries and the ability to have children (fertility). These blood draws are optional and the patient can still participate in the questionnaire portion of the study even if they choose not to have their blood drawn.

Eligibility

Inclusion Criteria:

        Subject Inclusion Criteria for Cohort of Premenopausal Women with Early Stage Breast Cancer
        and Lymphoma
          -  Women, 18 years of age and older
          -  Premenopausal women at time of diagnosis who have either been pregnant or had at least
             one menstrual period in the last 12 months
               -  Note: premenopausal women at time of diagnosis who have not been pregnant or have
                  not had at least one menstrual period in the last 12 months are able to
                  participate only if they have had an intrauterine device (IUD) in place within
                  the last 12 months.
          -  Women with newly diagnosed breast cancer (stage 0-III) who are within 1 month of
             starting systemic treatment or women with any aggressive lymphoma being treated with
             first line therapy with curative intent.
          -  Breast cancer patients with any receptor type
          -  English speaking
          -  Able to participate in the informed consent process
        Subject Inclusion Criteria for Tamoxifen Only Subset of Cohort of Premenopausal Women with
        Early Stage Breast Cancer and Lymphoma
          -  Women, 18 years of age and older.
          -  Premenopausal women at time of diagnosis who have either been pregnant or had at least
             one menstrual period in the last 12 months
               -  Note: premenopausal women at time of diagnosis who have not been pregnant or have
                  not had at least one menstrual period in the last 12 months are able to
                  participate only if they have had an intrauterine device (IUD) in place within
                  the last 12 months.
          -  Women with newly diagnosed breast cancer (stage 0-III) who have not yet started
             treatment and are planning to start Tamoxifen as their only form of systemic treatment
             within one month
          -  Breast cancer patients with any receptor type
          -  English speaking
          -  Able to participate in the informed consent process
        Subject Inclusion Criteria for Cohort of Postmenopausal Women with Early Stage Breast
        Cancer and Lymphoma
          -  Women, 18 years of age and older.
          -  Postmenopausal women at time of diagnosis who have been without period for ≥ 2 years.
          -  Women with newly diagnosed breast cancer (stage 0-III) who are within 1 month of
             starting systemic treatment or women with any aggressive lymphoma being treated with
             first line therapy with curative intent.
          -  Breast cancer patients with any receptor type
          -  English speaking
          -  Able to participate in the informed consent process
        Exclusion Criteria:
        Subject Exclusion Criteria for both Pre and Postmenopausal Women with Early Stage Breast
        Cancer and Lymphoma
          -  Active secondary cancer requiring cytotoxic chemotherapy
          -  Prior systemic treatment for a malignancy