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Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications

Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications

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Phase N/A
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Overview

To evaluate glaucoma patients' response to treatment with Xiidra, an FDA-approved drug for ocular surface discomfort, which will be prescribed as standard of care treatment.

Description

To assess glaucoma patients' response to treatment with Xiidra (Lifitegrast ophthalmic solution) 5% for ocular surface discomfort caused, in part, by topical glaucoma antihypertensive medications.

Eligibility

Inclusion Criteria:

  • Currently using one or more topical glaucoma antihypertensives
  • Self-described symptoms of ocular surface discomfort
  • Xiidra is being prescribed as part of the subject's standard care

Exclusion Criteria:

  • History of glaucoma filtration surgery, history of ocular surface surgery (pterygium, conjunctivoplasty, etc.),
  • current use of topical cyclosporine
  • current use of topical steroids
  • incisional ocular surgery within 6 months

Study details
    Glaucoma
    Ocular Surface Disease

NCT04354545

University of California, Los Angeles

13 May 2026

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