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Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma

Recruiting
18 years of age
Both
Phase N/A

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Overview

Adrenocortical carcinoma (ACC) is a rare and heterogeneous malignancy with poor prognosis. Surgical resection of the tumor is the treatment of choice. However, even after complete resection more than 80 % of patients will experience recurrence of disease. Therefore, new treatment options are urgently needed. This pre-clinical study try to lay the foundations for a successful immunotherapy in patients with ACC.

Eligibility

Inclusion Criteria:

  • patients with histological proven adrenocortical carcinoma
  • healthy persons as control group
  • Life expectancy > 6 months

Exclusion Criteria:

  • autoimmune diseases
  • severe clinical condition

Study details

Adrenocortical Carcinoma, Cushing's Syndrome

NCT00457587

University of Wuerzburg

26 May 2024

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