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Feasibility Study Aiming at Pre-Analytical Standardization of Whole Blood Processing for Liquid Biopsy Applications

Recruiting
18 years of age
Both
Phase N/A

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Overview

The goal of this feasibility study is to evaluate a new sample preparator called See.d.

After blood processing the instrument will produce a set of slides and a tube of plasma. These outputs could be used in further analysis in liquid biopsy applications.

Description

This feasibility study aims at the evaluation of a new instrument called See.d , to be used in conjunction with its accessories, Smart Bio Surface (SBS) slides and reagents, for preparation of cytological samples (seeded on SBS slides) and plasma from fresh whole blood (within 4-6 hours from collection).

Blood samples will be collected from healthy volunteers and will be used to test See.d performances. Moreover the possibility of develop a new version of the instrument with increased processing capability and to develop and optimize analytical protocols for liquid biopsy applications will be evaluated as exploratory objectives.

The only study procedure will be the collection of a blood sample from each participants; during this study 200 participants will be enrolled.

For its feasibility nature, no formal statistics has been planned for this study.

Eligibility

Inclusion Criteria:

  • Participants are willing and able to give and sign a written informed consent
  • Aged 18 or above

Exclusion Criteria:

  • Ongoing infections requiring antibiotic or antiviral treatment
  • Known hemostasis/coagulation disorder
  • Known Pregnancy

Study details

Healthy Participants

NCT05942066

Tethis S.p.A.

26 January 2024

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