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Exploring Biomarkers of the Carcinogenesis of Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas

Exploring Biomarkers of the Carcinogenesis of Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas

Recruiting
90 years and younger
All
Phase N/A
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Overview

This is a prospective, open large cohort study to explore biomarkers for detecting early carcinogenesis of IPMN.

Description

This prospective study was designed to explore biomarkers for detecting early carcinogenesis of IPMN. This study intends to prospectively and continuously enroll IPMN patients, and regularly collect biological samples including blood, urine, feces and saliva. We aimed to detect biomarkers which can predict the carcinogenesis of IPMN by multi-omics. The primary endpoint is the predictive accuracy of biomarkers for IPMN malignant transformation. The probability of IPMN malignant transformation , rates of surgical resection and survival after surgery are secondary endpoints.

Eligibility

Inclusion Criteria:

  • clinically diagnosed as IPMN;
  • without other malignant tumor;
  • agree to sign informed consent.

Exclusion Criteria:

  • with mental disorders which can affect cognition and cooperation;
  • with serious blood diseases or taking drugs that can affect peripheral blood

Study details
    Intraductal Papillary Mucinous Neoplasm

NCT05433935

Zhejiang University

26 January 2024

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