Overview
The objective of the study is to construct a noninvasive approach 68Ga-ACN376 PET/CT to detect the CLDN18.2 expression of tumor lesions in patients with Solid tumors and to identify patients benefiting from CLDN18.2 targeting treatment.
Eligibility
Inclusion Criteria:
- 1\. Aged \>18 years old; ECOG 0 or 1;
- 2\. Patients with solid tumors;
- 3\. Has at least one measurable target lesion according to Response Evaluation Criteria in Solid Tumors (RECIST V1.1);
- 4\. life expectancy \>=12 weeks.
Exclusion Criteria:
- 1\. Significant hepatic or renal dysfunction;
- 2\. Is pregnant or ready to pregnant;
- 3\. Cannot keep their states for half an hour;
- 4\. Refusal to join the clinical study;
- 5\. Suffering from claustrophobia or other mental diseases;
- 6\. Any other situation that researchers think it is not suitable to participate in the experiment.
