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The Effect of Combined Surgery in Management of Congenital Pseudarthrosis of Tibia

Recruiting
2 - 18 years of age
Both
Phase N/A

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Overview

The study aims to evaluate the clinical result of Combined Surgery in Management of Congenital Pseudarthrosis.

Description

The study aims to evaluate the clinical result of Combined Surgery in Management of Congenital Pseudarthrosis. The combined surgery includes sleeve resection of the pathological soft tissues, retrograde intramedullary rodding, packaged lilac bone autograft,and appliance of llizarov external fixation device. Bone uion rate,average time of healing, Healing index, ankle valgus, limb length discrepancy, tibia axis alignment are recorded and evaluated.

Eligibility

Inclusion Criteria:

  • The inclusion criteria consists of patients with congenital pseudarthrosis of Tibia

Exclusion Criteria:

  • Patients are complicated with mental, neurological disorders (such as hypoxic-ischemic encephalopathy, epilepsy and dementia) or significant barriers to growth.
  • Patients with pseudarthrosis of tibia caused by trauma, tumor,infection, etc
  • Children are complicated with dysfunction of liver and kidney , blood disorders, immune deficiency disease and ECG abnormalities.
  • Parents refused further treatment.

Study details

Congenital Pseudarthrosis of Tibia

NCT02640040

Hunan Children's Hospital

26 January 2024

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