Overview
This study is a multicenter prospective clinical study that aims to evaluate the predictive value of preoperative PET-CT results (such as SUV uptake, size of tumor lymph nodes, and differences in FDG uptake compared to surrounding tissues) for lymph node metastasis in patients with non-small cell lung cancer. During surgery, all patients underwent systematic mediastinal lymph node dissection. The final pathological results were used to assess the predictive value of PET-CT for segment-specific lymph node metastasis.
Eligibility
Inclusion Criteria:
- Solitary tumor, or multiple tumors with only ground-glass nodules (GGNs) apart from the primary lesion.
- Diameter of the primary lesion ≤5cm, with a CTR between 0.5 and 1.
- No enlarged mediastinal lymph nodes observed on preoperative contrast-enhanced CT.
- Pathological confirmation of non-small cell lung cancer (NSCLC) either before or during surgery.
- Systematic lymph node dissection performed during surgery.
- No prior radiotherapy or chemotherapy for initial treatment.
- No history of malignant tumors.
Exclusion Criteria:
- Locally advanced or distant metastasis.
- Pleural dissemination observed during surgery.
- History of malignant tumors.
- Received neoadjuvant therapy.
- Systematic lymph node dissection not performed during surgery.
- Histopathological examination reveals lung malignancies other than non-small cell lung cancer (NSCLC).