Image

Quality of Recovery From Mastectomy With and Without PECS Blocks

Quality of Recovery From Mastectomy With and Without PECS Blocks

Not Recruiting
18-90 years
Female
Phase N/A

Powered by AI

Overview

This is a prospective observational study. Investigators want to understand post-operative recovery for patients undergoing mastectomy at NorthShore University HealthSystem. Some of these patients receive PECS blocks with Liposomal Bupivacaine and some do not receive a block. Investigators want to know whether patients who receive a block have better post operative recovery and pain control than patients who do not receive one. Investigators also want to understand whether PECS blocks with Liposomal Bupivacaine improves quality of recovery at 72 hours post operatively.

Description

Investigators plan to approach and consent 800 patients undergoing mastectomy, 400 with PECS blocks and 400 without. Investigators will assess their quality of recovery using the QoR 15 survey at 72 hours post operatively. In addition, investigators will also record VAS scores immediately postoperatively and at 24, 48, and 72 hours postoperatively. The study team will also calculate the total morphine equivalents (MMEs) required for each patient after 72 hours.

Eligibility

Inclusion Criteria:

        Must be female Must be >18 years old and < 90 years old Must be able to consent in English
        or Spanish May or may not have breast cancer (prophylactic mastectomy) Must be undergoing
        unilateral or bilateral mastectomy of any type May choose to proceed with or without breast
        reconstruction
        Exclusion Criteria:
          -  Allergy to all narcotic or local anesthetic medications Intake of any chronic opioids
             or pain medications preoperatively for a chronic condition or chronic use.
        Subjects who received PECS blocks but whose block failed or is deemed not effective by an
        anesthesia provider as indicated by postoperative evaluation exam.
        Vulnerable subjects (children, prisoners, pregnant women)

Study details
    Post Operative Pain
    Quality of Recovery After Mastectomy

NCT05795413

NorthShore University HealthSystem

21 November 2025

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.