Overview
The purpose of this study is to learn more about the factors that influence decision-making before surgery (distress about cancer and/or reproductive concerns) and the possibility of regret after surgery.
Eligibility
Inclusion Criteria:
- Women aged ≥ 18 and ≤ 50 years
- Premenopausal
- Endometrioid histological diagnosis
- Scheduled for surgical intervention at MSKCC
- FIGO grade 1-2, clinical stage I
- Disease confined to uterus, no clear evidence of deep (≥50%) myoinvasion on imaging (MRI preferred, ultrasound optional)
- Normal ovaries on preoperative imaging
- Able to provide informed consent
- English-speaking
Exclusion Criteria:
- Known Lynch syndrome
- Prior bilateral oophorectomy
- Personal history of hormone receptor-positive breast carcinoma
- Increased risk of ovarian cancer identified on the basis of family or personal history
- Women currently on hormonal contraception, letrozole, or tamoxifen may not opt-in to AMH
- Women who recently underwent ovarian stimulation within the past 3 months may not opt-in to AMH
- Women who have pituitary dysfunction (or any pituitary disorders) may not opt-in to AMH
- Women who completed chemotherapy within <12 months may not opt-in to AMH