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Intraoperative Frozen Section Pathology to Guide Surgical Treatment for Lung Adenocarcinoma (ECTOP-1014)

Recruiting
years of age
Both
Phase N/A

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Overview

This study is one of Eastern Cooperative Thoracic Oncology Projects (ECTOP-1014). The goal of this clinical trial is to confirm the concordance rate between intra-operative frozen section pathological diagnosis and post-operative paraffin embedded pathological diagnosis, and use this result to guide surgical treatment for early stage (cT1N0M0) lung adenocarcinomas.

Eligibility

Inclusion Criteria:

  • Patients who sign the informed consent form and are willing to complete the study according to the study protocol;
  • No previous history of cancer or pulmonary surgery;
  • Solitary lesions or multiple lesions with only one not manifesting as pure ground-glass opacity (GGO) on CT scan;
  • Peripheral clinical T1N0M0 patients that are eligible for surgery;
  • Non-small cell lung cancer is pathologically diagnosed before or at surgery;
  • No radiation therapy or chemotherapy before surgery.

Exclusion Criteria:

  • Patients with clinical stages other than T1N0M0;
  • The lesion cannot be completely resected;
  • Previous history of cancer;
  • Patients having received radiation therapy or chemotherapy.

Study details

Lung Adenocarcinoma, Surgical Procedure, Unspecified, Pathology

NCT05794698

Fudan University

25 January 2024

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