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MPM Medical CoMatryx Surgical Bovine Collagen Study

Recruiting
18 - 85 years of age
Both
Phase N/A

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Overview

The objective of this prospective enrollment study is to collect data confirming safety, performance and clinical benefits of the CoMatryx Surgical Collagen powder at a minimum 1-year follow-up and compare it to a historical control group who did not receive the product at the time of surgery.

The primary objective is to confirm safety and clinical benefits of the product. This will be assessed by recording the rate of wound healing and incidence and frequency of wound care related complications. Relationship of complications to the product should be specified.

Description

The CoMatryx Surgical Collagen powder is a soft tissue repair product made of 100% Type I Bovine collagen. It is non-hydrolyzed and not cross-linked chemically. It is biocompatible, biodegradable and free of synthetics. The product does not have any specific storage requirements.

The CoMatryx Surgical Collagen powder provides a physiologically favorable environment to promote healing at the wound site. When administered, the powder conforms to the wound site and forms a gelatinous occlusive barrier. Along with providing 19 amino acids directly to the wound site it also occludes live nerve endings reducing pain. Treating the wound with the CoMatryx Surgical Collagen powder provides the non-hydrolyzed collagen wound surface promoting autolytic debridement. The powder is effective in all phases of wound healing and can be delivered with antibiotics in areas where there may be a cavity. This product has FDA 510(k) clearance for surgical wounds, full thickness wounds, traumatic wounds and skin tears.

Eligibility

Inclusion Criteria:

  • • Subjects must be 18 years of age or older
    • Subject must be willing and able to sign IRB approved informed consent
    • Subject must have a BMI of 35 or higher
    • Surgical approach of only ASI (anterior supine)
    • Primary total hip arthroplasty
    • Revision total hip arthroplasty

Exclusion Criteria:

  • • Subjects more than 85 years of age
    • Subjects who will be or have undergone bilateral total hip replacements
    • Subject is known to be pregnant or nursing
    • Subject is an alcohol or drug abuser
    • Subject has a psychiatric illness or cognitive deficit that will not allow for proper informed consent

Study details

Surgical Wound, Healed

NCT04407364

MPM Medical

25 January 2024

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