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Quebec Lung Cancer Screening PLUS Trial

Quebec Lung Cancer Screening PLUS Trial

Non Recruiting
55-74 years
All
Phase N/A

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Overview

Does an educational intervention for untreated COPD and cardiovascular disease which is integrated in an existing lung cancer screening program improve guideline concordant medication adherence at 12 months

Eligibility

Inclusion Criteria:

  • Patient screened for lung cancer as part of the Quebec Lung Cancer Demonstration project by low dose CT scan of the chest.
  • Cardiovascular aim: mild to severe CAC identified on low dose CT, not on guideline recommended lipid-lowering therapy.
  • COPD aim: diagnosed with COPD, symptomatic (mMRC >=1 or CAT>= 10) and untreated, or not on first line guideline recommended therapy for COPD.

Exclusion Criteria:

  • Any participant with a high suspicion of lung cancer, defined as Lung-RADS (Lung Imaging Reporting and Data System) 3 or 4, as this is an inopportune time to initiate new medical therapies.
  • Cardiovascular aim: Absent CAC, known clinical atherosclerosis, known former heart surgery, Diabetes Mellitus.
  • COPD aim: asymptomatic, or already on appropriate first line COPD therapy.

Study details
    COPD
    Coronary Artery Calcification

NCT05444062

Nicole Ezer, MD, FRCPC, MPH

20 August 2025

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