Overview
This is a double-masked, placebo-controlled study which will determine the action of NCX 470 ophthalmic solution, 0.1% on aqueous humor dynamic parameters in healthy volunteers or subjects with OHT.
Eligibility
Inclusion Criteria:
- ≥18 years of age
- Either gender
- Subjects without glaucoma
- Qualifying IOP at Screening Visit
Exclusion Criteria:
- Narrow anterior chamber angles or disqualifying central corneal thickness in either eye
- Clinically significant ocular disease in either eye
- Uncontrolled systemic disease
- Serious hypersensitivity to topical anesthetic eye drops
- Subjects with a known hypersensitivity or contraindications to any of the ingredients in the study medications
