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Predicting Post Extubation Stridor After Maxillomandibular Fixation

Predicting Post Extubation Stridor After Maxillomandibular Fixation

Recruiting
18 years and older
All
Phase N/A

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Overview

Endotracheal intubation can induce laryngotracheal injury which results in narrowing of the airway due to edema of the glottis. This can increase the risk of development of post-extubation stridor (PES)

Description

Ultrasound (US) is a useful and non-invasive tool for the evaluation of vocal cords and laryngeal morphology in intubated patients. The laryngeal air-column width (LACW), Laryngeal air column width difference (LACWD), and laryngeal air-column width ratio (LACWR) measured by ultrasound can potentially identify patients at risk of post-extubation stridor, in whom caution should be taken after extubation.

The cuff-leak test can predict successful extubation through using the difference between the expired tidal volume with the cuff inflated and with the cuff deflated; the higher the leak, the lower the likelihood that post-extubation stridor will occur.

Eligibility

Inclusion Criteria:

  • Adult patients (\>18 years)
  • American Society of Anesthesiologists status I and II
  • undergoing elective maxillomandibular fixation surgeries under general anesthesia with nasal endotracheal intubation

Exclusion Criteria:

  • patients' refusal
  • pregnant females
  • patients with body mass index \<18.5 or ≥ 35 kg/m2
  • risk of aspiration
  • cardiorespiratory disorder
  • neuromuscular disease
  • uncontrolled diabetes mellitus
  • gastrointestinal bleeding
  • on chronic steroid therapy
  • intubated patients or were intubated or had upper airway infection within 1 week prior to surgery
  • history of any pathology, radiotherapy or surgery in the neck
  • had difficult laryngeal US plane (as neck wound)

Study details
    Stridor
    Larynx Edema

NCT05839756

Mansoura University

14 May 2026

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