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Balloon Catheter Combined With Oxytocin Induction Among the Pregnant Women With Previous Cesarean Section

Balloon Catheter Combined With Oxytocin Induction Among the Pregnant Women With Previous Cesarean Section

Non Recruiting
20-40 years
Female
Phase N/A

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Overview

This study is a multi-center, prospective, observational clinical trial study. 924 full-term pregnant women will be enrolled as subjects, and the ratio of eligible subjects in the two groups is 1:1. In the prior cesarean section group, pregnant women with one previous cesarean section who are willing to try to the trial of labor after cesarean (TOLAC) and in accordance with the criteria according to the 2016 China vaginal birth after cesarean (VBAC) clinical management guidelines will be enrolled and recorded by our homemade registration form of TOLAC. In the control group, pregnant women after 39 weeks of gestation without vaginal labor contraindications will be enrolled. Whether in the experimental group or the control group, their cervical bishop score was less than 6 points, and they all will be induced by balloon catheter + oxytocin. After 96h, their final delivery mode will be recorded. In the following 42 days postpartum, their complications and the neonatal outcome will be followed up.

Eligibility

Inclusion Criteria:

  1. Volunteers sign the informed consent;
  2. Age: 20-40 years;
  3. Singleton, a cephalic presentation;
  4. No contradiction to vaginal delivery; 5.39~42 weeks.

Exclusion criteria:

  1. Konwn contraindication to vaginal delivery or severe complications;
  2. Multiple gestation;
  3. Uterine malformation;
  4. Severe psychiatric disorder;
  5. Without family's support.

Study details
    Trial of Labor After Cesarean
    Vaginal Birth After Cesarean
    Bishop Score
    Failed Mechanical Induction
    Balloon Catheter for Labor Induction
    Unfavorable Cervix

NCT05246761

The First Affiliated Hospital with Nanjing Medical University

20 August 2025

FAQs

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