Overview
Documenting efficiency of SBRT in the management of epidural spinal metastases from solid tumors
Description
The department of radiotherapy in UZLeuven recently included Stereotactic Body Radiotherapy (SBRT) in the standard of care for the management of patients with spinal metastases. The aim of this study is to prospectively document neurological outcome, performance and quality of life following surgery + SBRT for spinal metastases with imminent / actual spinal cord compression, and compare outcomes with the historical cohort of the UZLeuven patients included in the Global Spine Tumor Study Group database between 2011 and 2019 in whom prospective neurological, performance and quality of life outcomes were collected following surgery + conventional radiotherapy
Eligibility
Inclusion Criteria:
- Radiological diagnosis of spinal metastasis from solid tumor with epidural imminent or actual spinal cord compression, with or without neurological deficits. Patients will be scheduled for surgery + SBRT. If contra-indications preclude surgery and only SBRT is performed, patients will still be included.
- Written informed consent to participate in the study must be obtained from the subject or proxy /legal representative
- Males and females > 18 years
Exclusion Criteria:
- Any concomitant condition or disease which, in the opinion of the investigator, would affect the reliability of the collected data.
- Patients that had previous radiotherapy on the index spinal level without the possibility for additional SBRT at that particular level.