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CGM Use in Preterm Infants

Recruiting
- 72 years of age
Both
Phase N/A

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Overview

Preterm infants (gestational age (GA) at birth < 31 weeks) admitted to the University of Minnesota Masonic Children's Hospital NICU will have a Dexcom G6 sensor Continuous Glucose Monitor (CGM) placed shortly after consent and wear the device for up to 10 days. The low alarm threshold will be set at 60 mg/dL or 80mg/dL (depending on whether they are receiving continuous insulin) to detect the potential for hypoglycemia. A suggestion will be made to the clinical team to draw a blood glucose to correlate with CGM values ≤60 mg/dL and the infant will be treated according to Neonatal Intensive Care Unit (NICU) protocol for corroborating blood glucose levels. Infants will also be monitored per current NICU protocol (blood glucose checks every 1-2 hours while on insulin) and treated accordingly. Clinical data and long-term growth, body composition and neurodevelopmental outcomes will be recorded.

Eligibility

Inclusion Criteria:

  • preterm infants (gestational age (GA) at birth < 31 weeks)
  • admitted to the University of Minnesota Masonic Children's Hospital Neonatal Intensive Care Unit
  • written informed consent can be secured from a parent within 96 hours of birth.

Exclusion Criteria:

  • Infants born at ≥31 weeks GA
  • infants with a prenatally diagnosed clinical or genetic condition (other than prematurity) that is known to affect growth rate, adiposity, or neurocognitive development
  • children experiencing severe birth asphyxia,
  • children enrolled in another nutritional study,
  • children likely to be transferred out of the NICU

Study details

Very Low Birth Weight Infant, Very Preterm Maturity of Infant, Hyperglycemia

NCT05436925

University of Minnesota

25 January 2024

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