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SynerFuse Spinal Fusion and Neuromodulation Proof of Concept Study

Recruiting
21 - 80 years of age
Both
Phase N/A

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Overview

The purpose of the study is to evaluate the safety and tolerability of DRG stimulation when placing a neurostimulator during the same procedure as implantation of spinal fixation with or without interbody cage systems in patients with chronic back and/or leg pain requiring single level spinal fusion.

Eligibility

Inclusion Criteria:

  • Indicated for a single level or two level adjacent spinal fusion having back pain and radiculopathy
  • Have been diagnosed with chronic, intractable pain of the lower back and/or leg refractory to conservative therapy for at least 3 of months
  • At least 6 months since last surgical procedure on the spine
  • Be 21 years of age or older at the time of enrollment
  • Be willing and capable of giving informed consent
  • Be willing and able to comply with study-related requirements

Exclusion Criteria:

  • Any prior spinal fusion at index or adjacent level
  • Pregnant
  • Have a life expectancy of less than 1 year
  • Be concomitantly participating in another clinical study
  • Be involved in an injury claim under current litigation
  • Baseline narcotic use of ≥ 100 MME per day
  • Significant untreated addiction to dependency producing medications
  • Current active implantable medical device
  • Cancer
  • Have osteoporosis
  • Active infection
  • Allergies to system components
  • AGE > 80
  • Expected need to undergo MRI imaging in the future
  • Other significant comorbidities

Study details

Spinal Fusion, Radiculopathy Lumbar, Chronic Pain

NCT04054401

SynerFuse, Inc

25 January 2024

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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