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Benefit of Permanent Stimulation of the Left Branch of the His Bundle Versus Right Ventricular Stimulation After Atrioventricular Node Ablation for Rapid Atrial Fibrillation

Recruiting
18 years of age
Both
Phase N/A

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Overview

The objective of the study is to evaluate the functional benefit of left bundle branch of His pacing compared to right ventricular pacing in patients implanted with a pacemaker prior to a atrioventricular node ablation procedure for rapid atrial fibrillation

Eligibility

Inclusion Criteria:

        1/ Pacemaker implanted patient with LBTP lead and back-up right ventricular lead who
        subsequently underwent successful atrioventricular node ablation for rapid AF 2) NAV
        ablation procedure performed less than 15 days ago 3) Age ≥ 18 years 4) Woman of
        childbearing age with effective contraception (estrogen-progestin or intrauterine device or
        tubal ligation) for at least 1 month and for the duration of the study, and a negative
        urine pregnancy test by B-HCG at inclusion Or, Postmenopausal woman: confirmatory diagnosis
        (non-medically induced amenorrhea for at least 12 months prior to the inclusion visit).
        5) Membership of a social security scheme 6) Patient follow-up feasible 7) Patient has read
        and understood the information leaflet and signed the informed consent form
        Exclusion Criteria:
          1. Impairment of autonomy such that a maximal cardiorespiratory effort test (VO2 Max
             test) cannot be performed under good conditions (ADL scale < 5).
          2. LVEF < 40% at inclusion
          3. Person deprived of liberty by an administrative or judicial decision, or person under
             court protection, sub-guardianship or curatorship.
          4. Patient participating in another interventional trial
          5. Any history of illness or psychological or sensory abnormality likely to prevent the
             subject from fully understanding the conditions required for participation in the
             protocol, or from giving informed consent.
          6. Pregnant, parturient or breast-feeding women, or those without proven contraception

Study details

Atrial Fibrillation Rapid

NCT06061978

University Hospital, Rouen

25 January 2024

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