Overview
Magnetocardiography (MCG) is a promising noninvasive and accurate method for detecting cardiac abnormalities. However, the results of MCG cannot be evaluated without defined reference intervals. This is a multicenter cross-sectional study designed to establish reference values for MCG parameters healthy adults in China.
Eligibility
Inclusion Criteria:
- Age 18 years or older.
- Those with no hospitalization for any reason in the 6 months prior to the study.
- Those who are not currently taking any prescribed medications.
- Those with no history of cardiovascular diseases, including coronary artery disease, structural heart disease, arrhythmia, heart failure, stroke, pulmonary embolism, aortic coarctation, or peripheral arterial disease.
- Those with no risk factors for cardiovascular diseases, including hypertension, diabetes mellitus, hyperlipidemia.
- Those with no history of smoking (previous non-smoking or smoking cessation >6 months).
- Those with no excessive alcohol consumption (average daily alcohol consumption <3 drinks, 1 drink = beer 355mL / white wine 44mL / red wine 118mL).
- Signed informed consent.
Exclusion Criteria:
- Those with body mass index >28kg/m2 or <18kg/m2.
- Those with resting heart rate <50 beats/min, or >110 beats/min.
- Those with resting systolic blood pressure ≥ 140 mmHg, and/or diastolic blood pressure ≥ 90 mmHg.
- Those with fasting blood glucose ≥7 mmol/L, and/or random blood glucose ≥11.1 mmol/L.
- Those with total cholesterol ≥6.2 mmol/L or low-density lipoprotein cholesterol ≥4.1 mmol/L.
- Those with abnormal electrocardiograms, such as arrhythmias, ST-T changes, and pathologic electrical axis deflections.
- Those with cardiac ultrasonographic pathologic findings, such as left ventricular hypertrophy, left ventricular dilatation, abnormal ventricular wall motion, and valvular regurgitation or stenosis of more than mild degree.
- Those with respiratory diseases, kidney diseases, liver diseases, endocrine diseases, anaemia or other blood diseases, connective tissue diseases, malignant tumors and other diseases.
- Professional athletes, pregnant or lactating women, psychological or psychiatric disorders such as depression.
- Those who are unable to perform magnetocardiography due to claustrophobia, etc., or those who are unable to cooperate with the corresponding examinations required by the study for various reasons.