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Pharmacologic Effect for Female Overactive Bladder Syndrome: Mirabegron Versus Solifenacin

Recruiting
20 years of age
Female
Phase 3

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Overview

To assess the impact of mirabegron versus solifenacin on psychological distress, sexual function, bladder wall thickness and bladder blood flow.

Description

To assess the impact of mirabegron versus solifenacin on psychological distress, sexual function, bladder wall thickness and blood flow.

Eligibility

Inclusion Criteria:

  • Overactive bladder syndrome

Exclusion Criteria:

  • Allergy to mirabegron or solifenacin.
  • Patients with severe hypertension who are difficult to control, known urethral diverticulum, known bladder malignant tumors, urinary retention patients, gastric retention patients, uncontrolled angular glaucoma patients, dialysis patients, severe renal dysfunction , moderate liver dysfunction, use strong inhibitors of CYP3A4 such as ketoconazole.

Study details

Overactive Bladder Syndrome

NCT04023253

Far Eastern Memorial Hospital

25 January 2024

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