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Pathophysiology of Orthostatic Intolerance

Pathophysiology of Orthostatic Intolerance

Non Recruiting
18-80 years
All
Phase N/A

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Overview

The purpose of this study is to describe the mechanism of orthostatic intolerance, relying on cardiovascular physiological studies. The syndrome is of undetermined etiology, but the syndrome causes impairment of a number of young adults, females more than males, with symptoms of tachycardia, fatigue, lightheadedness, palpitations, blurred vision, chest discomfort, difficulty concentrating, and dizziness with the upright posture. It is believed that many different pathophysiological processes can give rise to this disorder.

Eligibility

Inclusion Criteria:

  • Orthostatic intolerance

Exclusion Criteria:

  • Inability or unwillingness to give informed consent

Study details
    Tachycardia
    Postural Orthostatic Tachycardia Syndrome

NCT00608725

Satish R. Raj

20 August 2025

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