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Dexmedetomidine Plus Low Dose Morphine Versus Standard Dose of Morphine in PCA in Children .

Recruiting
8 - 12 years of age
Both
Phase N/A

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Overview

The treatment of perioperative pain in children has been a topic of great interest to pediatricians, pediatric surgeons, and anesthesiologists for many years. Opioids are the most common analgesics used to manage acute postoperative pain in children and adults

Description

Patient-controlled analgesia (PCA) permits patients to self-administer small doses of opioid analgesics intravenously or subcutaneously at frequent intervals. PCA is used in the management of moderate-to-severe pain. Patient-controlled analgesia (PCA) is now used in children as young as 5 yr for the treatment of postoperative pain.

Eligibility

Inclusion Criteria:

  1. ASA I & II of both sex.
  2. Age between 8 and 12 years.
  3. Patients scheduled for exploration surgery under general anesthesia.

Exclusion Criteria:

  1. Parents refused to give consent.
  2. Patients with history of allergy to morphine or dexmedetomidine.
  3. Mental disorders.
  4. Unsuitability for extubation.
  5. Comorbidities as cardiac, pulmonary and obstructive sleep apnea.
  6. children with chronic opioid use for > 3 monthes

Study details

PCA, Children, Dexmedetomidine, Morphine

NCT05688371

Beni-Suef University

14 October 2025

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