Overview
The purpose of this prospectively enrolling trial is to assess long-term cognitive outcomes of patients undergoing surgery for resection of a meningioma associated with the frontal and temporal lobes.
Description
This study will look at patients who are undergoing resection of a skull based meningioma, located in the frontal or temporal lobe, via craniotomy or via endoscopic endonasal approach. The study will compare cognitive function at baseline, at six weeks postoperatively and at one year postoperatively. The cognitive testing being done at baseline will be a clinical care set of assessments done by the speech language pathology team and will include the RBANS tests, the MoCA, PROMIS-29, and NeuroQOL-Cognitive Functions.
Eligibility
Inclusion Criteria:
- Subject has a meningioma associated with the frontal or temporal lobes
- Subject is scheduled to undergo open craniotomy or Endoscopic Endonasal surgery
- Subject is 18 years of age or older
- The subject must in the investigator's opinion, be psychosocially, mentally, and physically able to fully comply with this protocol including the required follow-up visits, the filling out of required forms, and have the ability to understand and give written informed consent
- Previous surgery will not exclude the patient as a new baseline cognitive evaluation will occur.
Exclusion Criteria:
- Patient is a prisoner
- Patient is 90 years of age or older
- Pregnant women
- Previous radiation to the brain