Overview
To evaluate the potential usefulness of 68Ga-PSMA-11 positron emission tomography/computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions, efficacy assessment and recurrence monitoring in various types of cancer.
Description
Subjects with various types of cancer underwent 68Ga-PSMA-11 PET/CT either for an initial assessment or for recurrence detection. Tumor uptake was quantified by the maximum standard uptake value (SUVmax). The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of 68Ga-PSMA-11 PET/CT were calculated.
Eligibility
Inclusion Criteria:
(i) adult population (aged 18 years or order); (ii) patients with suspected or new
diagnosed or previously treated malignant tumors (supporting evidence may include MRI, CT,
tumor markers and pathology report); (iii) patients who had scheduled 68Ga-PSMA-11 PET/CT
scan; (iv) patients who were able to provide informed consent (signed by participant,
parent or legal representative) and assent according to the guidelines of the Clinical
Research Ethics Committee.
Exclusion Criteria:
(i) patients with pregnancy; (ii) the inability or unwillingness of the research
participant, parent or legal representative to provide written informed consent.