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Anatomical and Functional Outcome of PSG Vs BMG for Urethral Substitution in Long Segment Anterior Urethral Strictures

Recruiting
5 years of age
Male
Phase N/A

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Overview

This study aims to compare the penile skin graft and buccal mucosal graft for substitution of long anterior urethral strictures using one-sided dorsal perineal approach.

Description

Since previous studies were:

  • Retrospective and very few were prospective randomized studies
  • Some studies were done on lichen sclerosis cases that have an adverse effect on the PSG outcome.
  • The follow-up duration was longer for PSG patients.
  • Stricture length was usually longer for PSG cases.

This study aims to compare the PSG and BMG for substitution of long anterior urethral strictures using one-sided dorsal perineal approach.

The investigators hypothesize that:

❶ Conducting a well-designed prospective, randomized study can help identify which technique is better than the other.

❷ Using the one-side dorsal approach can improve the outcomes of both techniques and identify their advantages and disadvantages.

Eligibility

Inclusion Criteria:

  • The study will include patients with long segment anterior urethral stricture (>2 cm).

Exclusion Criteria:

  • Urethro-cutaneous fistula, urethral abscess or diverticulum.
  • A scarred and unsalvageable urethral plate or scarred perineum.
  • Lichen sclerosis (Balanitis xerotica obliterans).
  • Unhealthy/unavailable buccal mucosa.

Study details

Anterior Urethral Stricture, Male

NCT06056856

Al-Azhar University

25 January 2024

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