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Clinical Study on Treatment of Chronic Persistent Bronchial Asthma

Recruiting
18 - 65 years of age
Both
Phase 2

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Overview

Investigators aimed to evaluate the clinical efficacy of integrated traditional Chinese and Western medicine in the treatment of asthma, and to further optimize the prescription of Chinese medicine treatment.

Description

The incidence of asthma in China is high and the rate of control is low. Traditional Chinese medicine has a long history of treating asthma, and has a good clinical curative effect.The purpose of this study is to evaluate the clinical efficacy of traditional Chinese medicine in the treatment of asthma, and to further optimize the prescription of Chinese medicine treatment.

In this study, investigators recruited chronic persistent asthma participants, and gave the corresponding western medicine background treatment and traditional Chinese medicine treatment program for 28 days.Participants will undergo a physical examination, lung function, blood and sputum collection.

Eligibility

Inclusion Criteria:

  • Patient diagnosed with chronic persistent asthma
  • Patients had positive bronchodilator reversibility test or positive bronchial challenge test or more than 50 parts per billion of FENO before
  • Conform to the predetermined 2 TCM Syndrome Types
  • Patients who have given written informed consent

Exclusion Criteria:

  • Smoking and continuous exposure to hazardous environment
  • With fever, or severity of intermittent state, high degree of sustained, or with respiratory failure, etc.
  • Pulmonary emphysema, chronic obstructive pulmonary disease, pulmonary emphysema, pulmonary heart disease, pneumonia, lung cancer and other lung diseases
  • Patients who are allergic to therapeutic medicine

Study details

Bronchial Asthma

NCT03228134

Shanghai University of Traditional Chinese Medicine

25 January 2024

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